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<h3 class='figure_identifier'>Steven A. Rothman, MD - AFib Treatment: General Population - Figure 8</h3>
<h2>Natural History of AFib</h2>


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      <p>The natural history of AFib usually begins with the risk factors that are associated with the arrhythmia, such as hypertension, coronary artery disease, heart failure, sleep apnea, and obesity.<span style='font-family: "Arial", "sans-serif";' mso-bidi-font-weight:bold\?="" mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA;="" Roman&quot;;="" New="" mso-fareast-font-family:&quot;Times="" Roman&quot;;mso-bidi-font-family:&quot;Times="" 12.0pt?=""><span class="ref_num">[53]</span> </span>These lead to changes within the atria, both in the muscular function of the heart, as well as in the electrical stability of the heart, and when this <span class='\"GRcorrect\"' gruiphraseguid='\"1171dc73-f337-4a8a-a8b8-70fd34dd17b9\"' grmarkguid='\"11517514-af2c-4445-80c9-a34dfc89245c\"' grcontextid='\"develop:0\"'>develops</span> into AFib, the presentation tends to be paroxysmal. &nbsp;Over time, as these changes progress, the arrhythmia becomes more persistent, and eventually the patient enters permanent AFib.</p>
<p><b>Rothman SA. <i>Am J <span class='\"GRcorrect\"' gruiphraseguid='\"a724bdc3-e227-4042-a8e0-089e20daabcc\"' grmarkguid='\"85b47add-c5f5-419a-a06b-fc6fada3b721\"' grcontextid='\"Med:0\"'>Med</span></i> 2013; 126: 00-00.</b><br class='\"aloha-end-br\"'></p>    </div>


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  <h2>References</h2>
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    <span class="ref_num">[53]</span> Anter E, Callans DJ, Wyse DG. Pharmacological and electrical conversion of atrial fibrillation to sinus rhythm is worth the effort. <i>Circulation.</i> 2009;120:1436-1443.  </p>
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