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<h3 class='figure_identifier'>James A. Reiffel, MD - Novel Oral Anticoagulants - Figure 54</h3>
<h2>Ischemic Stroke</h2>


<div class='figure_text' speaker='reiffelB' figure='54'>
      <P>This <B>Figure</B> presents a Forrest plot of the reduction in ischemic stroke by ITT analysis.<span class='ref_num'>[118]</span> As seen in the preceding Figures, only the higher dose of <SPAN class='\"GRnoSuggestion' grcontextid='\"dabigatran:0\"' grmarkguid='\"25cfb694-9b63-40cc-858d-19b6111521c9\"' gruiphraseguid='\"ac142d6b-d86b-4249-891a-aa771c7a40e9\"' grcorrect\?="">dabigatran</SPAN> produces a statistically significant (p=0<SPAN class='\"GRcorrect\"' grcontextid='\".:1\"' grmarkguid='\"c9d58261-4e25-4847-bae4-d32fb3022717\"' gruiphraseguid='\"ac142d6b-d86b-4249-891a-aa771c7a40e9\"'>.</SPAN>03) reduction, but again, all the other results lie along the line of “no difference” from <SPAN class='\"GRcorrect\"' grcontextid='\"warfarin:2\"' grmarkguid='\"fdfc8d34-78cc-4968-a345-4de00b6959a9\"' gruiphraseguid='\"ac142d6b-d86b-4249-891a-aa771c7a40e9\"'>warfarin</SPAN>, and it is the side effects more than the efficacy of <SPAN class='\"GRcorrect\"' grcontextid='\"warfarin:3\"' grmarkguid='\"0e444b63-b77b-4380-b58e-1434928e402b\"' gruiphraseguid='\"ac142d6b-d86b-4249-891a-aa771c7a40e9\"'>warfarin</SPAN> that presents so many problems with this drug, for physicians and patients.</P>
<P>&nbsp;<B><SPAN class='\"GRnoSuggestion' grcontextid='\"Reiffel:0\"' grmarkguid='\"68e5eada-cca6-4129-a88c-8c991b448551\"' gruiphraseguid='\"901b2585-dee2-40df-8b86-8fb8e3836659\"' grcorrect\?="">Reiffel</SPAN> JA. <I>Am J <SPAN class='\"GRcorrect\"' grcontextid='\"Med:0\"' grmarkguid='\"c3007679-2f0e-44ca-9dbd-07754a30709d\"' gruiphraseguid='\"1c78da0f-82c2-4d47-98dd-c0488bdbb408\"'>Med</SPAN></I> 2013; 126: 00-00.</B><BR class='\"aloha-end-br\"'></P>  </div>


  <div class='figure_references' speaker='reiffelB' figure='54'>
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  <a href="complete_references.php" class="noprint right resource_link buttonify" target_orig="_blank">Complete references for all slides</a>
  <h2>References</h2>
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    <span class="ref_num">[118]</span> Tendera M, Syzdół M, Parma Z. ARISTOTLE RE-LYs on the ROCKET. What&apos;s new in stroke prevention in patients with atrial fibrillation? <i>Cardiol J.</i> 2012;19:4-10.  </p>
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