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<h3 class='figure_identifier'>James A. Reiffel, MD - Novel Oral Anticoagulants - Figure 36</h3>
<h2>Pre-defined Populations in ROCKET AF</h2>


<div class='figure_text' speaker='reiffelB' figure='36'>
      <P>The previous Figure showed the results of the ITT analysis (ie, the results were analyzed on the basis of which drug each patient was prescribed). &nbsp;However there were 2 further pre-defined analyses (shown in this <B>Figure</B>): </P>
<UL>
<LI>safety-on-treatment (all people in the ITT population who got at least one dose of the drug) and </LI>
<LI>per-protocol (all patients in the safety population who did not have a major protocol violation, which was the overwhelming majority of the patients).<SPAN 1.4;\?="" line-height:="" 12pt;="" font-size:="" sans-serif;="" arial,=""></SPAN><span class='ref_num'>[97]</span></LI></UL>
<P>&nbsp;<B><SPAN class='\"GRnoSuggestion' gruiphraseguid='\"413727cc-fd02-4953-bf1d-e8d502022d6e\"' grmarkguid='\"f92d3497-7717-4e03-9260-ea991c02ebda\"' grcontextid='\"Reiffel:0\"' grcorrect\?="">Reiffel</SPAN> JA. <I>Am J <SPAN class='\"GRcorrect\"' gruiphraseguid='\"250802e9-a35c-4dc1-a4aa-ffa4be37b25b\"' grmarkguid='\"c467e07b-e6b6-4c5a-aef2-b9b4763f5357\"' grcontextid='\"Med:0\"'>Med</SPAN></I> 2013; 126: 00-00.</B><BR class='\"aloha-end-br\"'></P><SPAN style="FONT-FAMILY: 'Arial', 'sans-serif'" font-size: mso-bidi-font-weight:bold\?="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa;="" roman&quot;;="" roman&quot;;mso-bidi-font-family:&quot;times="" new="" mso-fareast-font-family:&quot;times="" 12.0pt?><B></B></SPAN>  </div>


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  <h2>References</h2>
    <p>
    <span class="ref_num">[97]</span> Patel MR, Mahaffey KW, Garg J, et al; the ROCKET AF Steering Committee, for the ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. <i>N Engl J Med.</i> 2011;365:883-891.  </p>
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