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<h3 class='figure_identifier'>James A. Reiffel, MD - Novel Oral Anticoagulants - Figure 27</h3>
<h2>Summary of Clinical Outcomes</h2>


<div class='figure_text' speaker='reiffelB' figure='27'>
      <P>This <B>Figure </B>summarizes the efficacy and safety outcomes of the higher, 150-mg dose of <SPAN class='\"GRnoSuggestion' grcontextid='\"dabigatran:0\"' gruiphraseguid='\"d3a64a33-9a24-4b12-84a0-7acdc4d3de92\"' grmarkguid='\"3e0ed22c-b6ed-497f-95d7-188775731716\"' GRcorrect\?>dabigatran</SPAN> versus <SPAN class='\"GRnoSuggestion' grcontextid='\"warfarin:1\"' gruiphraseguid='\"d3a64a33-9a24-4b12-84a0-7acdc4d3de92\"' grmarkguid='\"3b06bcf1-e6e1-4d0f-b259-4079d85e9ce3\"' GRcorrect\?>warfarin</SPAN> in the RE-LY trial.<SPAN style="FONT-FAMILY: 'Arial', 'sans-serif'" mso-bidi-font-weight:bold\? mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA; Roman&quot;; New Roman&quot;;mso-bidi-font-family:&quot;Times mso-fareast-font-family:&quot;Times 12.0pt? font-size:><span class='ref_num'>[96]</span> </SPAN>As seen in the in the Forrest plot, other than major GI bleeding everything favors <SPAN class='\"GRnoSuggestion' grcontextid='\"dabigatran:0\"' gruiphraseguid='\"915ea1c2-5205-4748-b525-0333eac0de06\"' grmarkguid='\"644c5973-a32c-4775-be65-46d8d5e4b088\"' GRcorrect\?>dabigatran</SPAN> over <SPAN class='\"GRcorrect\"' grcontextid='\"warfarin:1\"' gruiphraseguid='\"915ea1c2-5205-4748-b525-0333eac0de06\"' grmarkguid='\"98af6110-f1fc-4e7a-848a-02e7d2e6113e\"'>warfarin</SPAN> and superiority in terms of stroke reduction of all types of stroke.</P>
<P>&nbsp;<B><SPAN class='\"GRnoSuggestion' grcontextid='\"Reiffel:0\"' gruiphraseguid='\"925214df-8596-4f44-a65e-fdb89a0797e3\"' grmarkguid='\"3a12d4df-e415-4a7b-909e-2373becb89f1\"' GRcorrect\?>Reiffel</SPAN> JA. <I>Am J <SPAN class='\"GRcorrect\"' grcontextid='\"Med:0\"' gruiphraseguid='\"fe3f6731-96e0-41e0-8429-c2cc98517464\"' grmarkguid='\"c72d0db6-a815-4743-baf5-5240948c7c5a\"'>Med</SPAN></I> 2013; 126: 00-00.</B><BR class='\"aloha-end-br\"'></P>  </div>


  <div class='figure_references' speaker='reiffelB' figure='27'>
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  <a href="complete_references.php" class="noprint right resource_link buttonify" target_orig="_blank">Complete references for all slides</a>
  <h2>References</h2>
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    <span class="ref_num">[96]</span> Connolly SJ, Ezekowitz MD, Yusuf S, et al; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. <i>N Engl J Med.</i> 2009;361:1139-1151.  </p>
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