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<h3 class='figure_identifier'>Steven A. Rothman, MD - AFib Treatment: General Population - Figure 25</h3>
<h2>TTR = Risk Protection</h2>


<div class='figure_text' speaker='rothman' figure='25'>
      
      <p>This <b>Figure</b> illustrates a very simple concept: in this retrospective study of &gt;6,000 patients in the United Kingdom, freedom from <span class='\"GRcorrect\"' grcontextid='\"risk:0\"' grmarkguid='\"80ca4d44-c134-48cb-a637-25812730f19f\"' gruiphraseguid='\"9f98cb7c-7e65-4549-b749-0e77802deb66\"'>risk</span> of stroke is greatly increased <span class='\"GRcorrect\"' grcontextid='\"for:1\"' grmarkguid='\"8139e5a2-081b-4ea0-bdd0-28fb73357c6f\"' gruiphraseguid='\"9f98cb7c-7e65-4549-b749-0e77802deb66\"'>for</span> patients who are kept within the INR 2–3 therapeutic window between 70% and 100% of the time. &nbsp;This benefit decreases dramatically, however, when the %-time in therapeutic range (TTR) decreases to &lt;70%<span Arial,="" sans-serif;="" 12pt;="" 1.4;\?="">.</span><span class="ref_num">[75]</span></p>
<p><b>Rothman SA. <i>Am J <span class='\"GRcorrect\"' grcontextid='\"Med:0\"' grmarkguid='\"7eb4dfbc-9888-48e7-8a6d-600fb3c58295\"' gruiphraseguid='\"31a1bb99-6eb0-460e-87b4-a43275ce80ce\"'>Med</span></i> 2013; 126: 00-00.</b><br class='\"aloha-end-br\"'></p><span style='font-family: "Arial", "sans-serif";' 12.0pt?="" Roman&quot;;mso-bidi-font-family:&quot;Times="" mso-fareast-font-family:&quot;Times="" New="" Roman&quot;;="" mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA;="" mso-bidi-font-weight:bold\?=""></span>    </div>


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  <h2>References</h2>
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    <span class="ref_num">[75]</span> Morgan CL, McEwan P, Tukiendorf A, Robinson PA, Clemens A, Plumb JM. Warfarin treatment in patients with atrial fibrillation: observing outcomes associated with varying levels of INR control. <i>Thromb Res.</i> 2009;124:37-41.  </p>
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