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<h3 class='figure_identifier'>James A. Reiffel, MD - Novel Oral Anticoagulants - Figure 20</h3>
<h2>Reduced time to first stroke</h2>


<div class='figure_text' speaker='reiffelB' figure='20'>
      <P>The <B>Figure</B> shows the primary results of RE-LY.<span class='ref_num'>[96]</span><SPAN mso-bidi-font-weight:bold\\\?='\"\"' mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa;='\"\"' roman&quot;;='\"\"' roman&quot;;mso-bidi-font-family:&quot;times='\"\"' new='\"\"' mso-fareast-font-family:&quot;times='\"\"'></SPAN> <SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"0395fc66-8e3a-4a78-92db-cc1c66953544\\"\"' grmarkguid='\"\\"3e88155d-6158-4a2d-87e9-08be652d13ea\\"\"' grcontextid='\"\\"Dabigatran:0\\"\"' grcorrect\\\?='\"\"'>Dabigatran</SPAN> 150 bid (black line) had a statistically significantly lower probability of the composite endpoint of stroke and systemic embolism than did <SPAN class='\"\\"GRcorrect\\"\"' gruiphraseguid='\"\\"0395fc66-8e3a-4a78-92db-cc1c66953544\\"\"' grmarkguid='\"\\"19caa725-5d0d-418c-84cf-31b593780b0c\\"\"' grcontextid='\"\\"warfarin:1\\"\"'>warfarin</SPAN>. &nbsp;<SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"3056d18e-82a1-4755-8a16-f4364c5d9dd2\\"\"' grmarkguid='\"\\"7a3123c1-9585-4ad0-9698-0a02f3a7b2d3\\"\"' grcontextid='\"\\"Dabigatran:0\\"\"' grcorrect\\\?='\"\"'>Dabigatran</SPAN> 110 mg bid (dark blue line) was non-inferior to <SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"3056d18e-82a1-4755-8a16-f4364c5d9dd2\\"\"' grmarkguid='\"\\"6a98dbe4-cdee-41d9-bf65-5f89ec2db862\\"\"' grcontextid='\"\\"warfarin:1\\"\"' grcorrect\\\?='\"\"'>warfarin (light blue line)</SPAN>, with both of these latter two having a similar probability of endpoint events.</P>
<P>&nbsp;<B><SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"e0a4e6e1-1f28-4519-b25c-ef61583e096e\\"\"' grmarkguid='\"\\"3f7ff493-5118-496a-a2e9-0757484023f7\\"\"' grcontextid='\"\\"Reiffel:0\\"\"' grcorrect\\\?='\"\"'>Reiffel</SPAN> JA. <I>Am J <SPAN class='\"\\"GRcorrect\\"\"' gruiphraseguid='\"\\"2724cac4-be60-47f9-8147-26e0df7d2e60\\"\"' grmarkguid='\"\\"1d507093-55cd-4fa4-ab73-200013070e9b\\"\"' grcontextid='\"\\"Med:0\\"\"'>Med</SPAN></I> 2013; 126: 00-00.</B><BR class='\"\\"aloha-end-br\\"\"'></P>  </div>


  <div class='figure_references' speaker='reiffelB' figure='20'>
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  <a href="complete_references.php" class="noprint right resource_link buttonify" target_orig="_blank">Complete references for all slides</a>
  <h2>References</h2>
    <p>
    <span class="ref_num">[96]</span> Connolly SJ, Ezekowitz MD, Yusuf S, et al; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. <i>N Engl J Med.</i> 2009;361:1139-1151.  </p>
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