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<h3 class='figure_identifier'>Reiffel - Atrial Fibrillation and Stroke: Epidemiology - Figure 13</h3>
<h2>Stasis in the Left Atrial Appendage</h2>


<div class='figure_text' speaker='reiffelA' figure='13'>
      <P>This<B> Figure </B>shows potential <SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"da857ecb-92c2-4451-8a85-676e243694e6\\"\"' grmarkguid='\"\\"ecce7f53-6948-418e-9289-9dd8b0a5329d\\"\"' grcontextid='\"\\"prothrombotic:0\\"\"' grcorrect\\\?='\"\"'><SPAN class='\"GRnoSuggestion' gruiphraseguid='\"4a03de19-0e4d-4e99-9df5-c45b2c57fc56\"' grmarkguid='\"d484951a-2cc5-4f3b-b750-9166b5ffedd2\"' grcontextid='\"prothrombotic:0\"' GRcorrect\?>prothrombotic</SPAN></SPAN> mechanisms in AFib and it demonstrates the effect of left atrial stasis. &nbsp;So you can see as <SPAN class='\"\\"GRcorrect\\"\"' gruiphraseguid='\"\\"e0d9d94d-bf67-4a76-ad1a-79eefa107367\\"\"' grmarkguid='\"\\"f2b80fae-a7b5-4489-9b9f-3dc5a0134139\\"\"' grcontextid='\"\\"antegrade:0\\"\"'><SPAN class='\"GRcorrect\"' gruiphraseguid='\"dd5360f8-8d7e-4dd0-980a-45501cbc36da\"' grmarkguid='\"7a857756-1252-4af9-b434-364b6c412890\"' grcontextid='\"antegrade:0\"'>antegrade</SPAN></SPAN> flow velocity increases, the <SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"e0d9d94d-bf67-4a76-ad1a-79eefa107367\\"\"' grmarkguid='\"\\"16120168-0bbe-4d2b-b587-f7092538d2e8\\"\"' grcontextid='\"\\"annualized:1\\"\"' grcorrect\\\?='\"\"'><SPAN class='\"GRnoSuggestion' gruiphraseguid='\"dd5360f8-8d7e-4dd0-980a-45501cbc36da\"' grmarkguid='\"84f7e2b9-2afa-423f-b6a2-e0c842d12110\"' grcontextid='\"annualized:1\"' GRcorrect\?>annualized</SPAN></SPAN> risk of <SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"e0d9d94d-bf67-4a76-ad1a-79eefa107367\\"\"' grmarkguid='\"\\"ddd10351-f2d8-411b-93ff-d42930797815\\"\"' grcontextid='\"\\"cardioembolic:2\\"\"' grcorrect\\\?='\"\"'><SPAN class='\"GRnoSuggestion' gruiphraseguid='\"dd5360f8-8d7e-4dd0-980a-45501cbc36da\"' grmarkguid='\"39bafb6e-1ee4-449d-977a-0a04559c748d\"' grcontextid='\"cardioembolic:2\"' GRcorrect\?>cardioembolic</SPAN></SPAN> events decreases just going from left to right, so stasis is clearly a component of the risk profile <span class='ref_num'>[21]</span></P><SPAN style="FONT-FAMILY: 'Arial', 'sans-serif'" font-size: mso-bidi-font-weight:bold\? mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA; Roman&quot;; New Roman&quot;;mso-bidi-font-family:&quot;Times mso-fareast-font-family:&quot;Times 12.0pt?><B>&nbsp;<BR></B></SPAN>
<P><B><SPAN class='\"\\"GRnoSuggestion\"' gruiphraseguid='\"\\"b3625965-7cf7-4954-87dd-f5a5f560c469\\"\"' grmarkguid='\"\\"db9e5422-a143-4c6e-adf3-c0883bf0bd77\\"\"' grcontextid='\"\\"Reiffel:0\\"\"' grcorrect\\\?='\"\"'><SPAN class='\"GRnoSuggestion' gruiphraseguid='\"15b02d37-cd56-4b7e-a5be-d787ebcfd18d\"' grmarkguid='\"84fc248e-209b-4ac5-a2ff-5ae11eb6a36f\"' grcontextid='\"Reiffel:0\"' GRcorrect\?>Reiffel</SPAN></SPAN> JA. <I>Am J <SPAN class='\"\\"GRcorrect\\"\"' gruiphraseguid='\"\\"54836742-e124-4040-89ea-a20b990516ff\\"\"' grmarkguid='\"\\"be368af4-5752-4105-b6e3-5da2e875853c\\"\"' grcontextid='\"\\"Med:0\\"\"'><SPAN class='\"GRcorrect\"' gruiphraseguid='\"ad782d20-ab16-4f9f-a3d1-244388002577\"' grmarkguid='\"135caf26-dfc6-4cb9-8c23-69a640250e2f\"' grcontextid='\"Med:0\"'>Med</SPAN></SPAN></I> 2013; 126: 00-00.</B><BR class='\"\\"aloha-end-br\\"\"'></P>  </div>


  <div class='figure_references' speaker='reiffelA' figure='13'>
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  <a href="complete_references.php" class="noprint right resource_link buttonify" target_orig="_blank">Complete references for all slides</a>
  <h2>References</h2>
    <p>
    <span class="ref_num">[21]</span> Goldman ME, Pearce LA, Hart RG, et al. Pathophysiologic correlates of thromboembolism in nonvalvular atrial fibrillation: I. Reduced flow velocity in the left atrial appendage (The Stroke Prevention in Atrial Fibrillation [SPAF-III] study). <i>J Am Soc Echocardiogr.</i> 1999;12:1080-1087.  </p>
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