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<h3 class='figure_identifier'>William French, MD - Anticoagulation: Special Populations - Figure 12</h3>
<h2>Risk Factors and Efficacy</h2>


<div class='figure_text' speaker='french' figure='12'>
      
      <p>After the greater risk of <span class='\"GRnoSuggestion' GRcorrect\?="" grcontextid='\"thromboembolism:0\"' grmarkguid='\"658479f1-230e-454d-8c61-ee12a696a427\"' gruiphraseguid='\"37514b64-31b6-453c-9d79-8c964c004fc0\"'>thromboembolism</span> in women seen in the previous Figure, the good news in this <b>Figure</b>, from a pooled analysis of 5 randomized trials,<span style='font-family: "Arial", "sans-serif";' 12.0pt?="" Roman&quot;;mso-bidi-font-family:&quot;Times="" mso-fareast-font-family:&quot;Times="" New="" Roman&quot;;="" mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA;="" mso-bidi-font-weight:bold\?=""><span class="ref_num">[128]</span> </span><span class='\"GRcorrect\"' grcontextid='\"is:0\"' grmarkguid='\"7f508a9c-2517-4e29-a554-88c74ec824a3\"' gruiphraseguid='\"56666025-7b5c-4bef-bc0e-377516ec7e69\"'>is</span> that anticoagulation therapy with warfarin decreased the risk of stroke by 84% in women compared with only 60% in men. &nbsp;So importantly, the chance of a woman with AFib having a stroke or systemic emboli is higher, but the use of <span class='\"GRnoSuggestion' GRcorrect\?="" grcontextid='\"antithrombin:0\"' grmarkguid='\"d693e429-aedd-40bc-8de4-a086e0fc16e5\"' gruiphraseguid='\"ee88ec1e-21e3-4085-9950-47604e33b5b9\"'>antithrombin</span> therapy actually seems to confer greater benefit to females even than for men.</p>
<p><b>French WJ. <i>Am J <span class='\"GRcorrect\"' grcontextid='\"Med:0\"' grmarkguid='\"f2755e0c-9d69-4d2e-b74a-f8f901705762\"' gruiphraseguid='\"e38a305e-7a17-4809-a55f-17551031e9fd\"'>Med</span></i> 2013; 126: 00-00.</b><br class='\"aloha-end-br\"'></p>    </div>


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  <h2>References</h2>
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    <span class="ref_num">[128]</span> Atrial Fibrillation Investigators: Atrial Fibrillation, Aspirin, Anticoagulation Study; Boston Area Anticoagulation Trial for Atrial Fibrillation Study; Canadian Atrial Fibrillation Anticoagulation Study; Stroke Prevention in Atrial Fibrillation Study; Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Study Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. <i>Arch Intern Med.</i> 1994;154:1449-1457.  </p>
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