Shariat - Figure 35
Sarcomatoid Carcinoma (Carcinosarcoma)
FIG. 35: A second histologic variant is sarcomatoid carcinoma (carcinosarcoma).[40] These are biphasic tumors with a malignant spindle and epithelial cells. Grossly, many tumors present as polypoid masses. Nodal or distant metastases are frequent. The tumor is often understaged, has a poor prognosis, and many of these patients die very soon. The differential diagnosis from a true sarcoma and an invasive muscle tumor is essential. In most cases these patients with T1 bladder cancer are best treated with an immediate radical cystectomy.
References
[40]
Mochini M. Nat Rev Urol. In press