Fig. 01 -

Title Slide

Fig. 02 -

Disclosures

Fig. 03 -

Outline

Fig. 04 -

Hard-Wired

Fig. 05 -

Autonomic Nervous System

Fig. 06 -

Profile

Fig. 07 -

Modulation

Fig. 08 -

Humoral

Fig. 09 -

Plasma Graphs

Fig. 10 -

Sleep Stages

Fig. 11 -

Metabolic

Fig. 12 -

Orchestration

Fig. 13 -

Cerebral Glucose

Fig. 14 -

Take Home Message

Fig. 15 -

Sleep & Obesity

Fig. 16 -

Sleep in America

Fig. 17 -

Impact

Fig. 18 -

Leptin Graph

Fig. 19 -

Ad Lib Feeding

Fig. 20 -

Excessive Food Intake

Fig. 21 -

Meta-Analyses

Fig. 22 -

Insufficient Sleep

Fig. 23 -

Laboratory

Fig. 24 -

Insulin Sensitivity

Fig. 25 -

Insulin & Sleep

Fig. 26 -

Diabetes Risk

Fig. 27 -

Sleep Comparison

Fig. 28 -

Glucose Metabolism

Fig. 29 -

Normal Sleep

Fig. 30 -

Sleep Restriction

Fig. 31 -

Intracellular Response

Fig. 32 -

28% Increased Risk

Fig. 33 -

57% Increased Risk

Fig. 34 -

84% Increased Risk

Fig. 35 -

Diabetes Risk

Fig. 36 -

Non Sleep Factors

Fig. 37 -

Hypertension

Fig. 38 -

Nocturnal Blood Pressure

Fig. 39 -

CARDIA-Sleep Study

Fig. 40 -

Incident Hypertension

Fig. 41 -

Cross-Sectional Associations

Fig. 42 -

Longitudinal Associations

Fig. 43 -

Hypertension Risk

Fig. 44 -

Take Home Messages