Kamat - Figure 8
Many NMI tumors cluster with MIBC
FIG. 8: It is also true that there are many subtypes of non-muscle-invasive (NMI) disease. Many NMI tumors cluster with muscle-invasive bladder cancer, separate from their clustering within the group itself. This Figure shows that bladder cancer is heterogeneous, not only among muscle-invasive tumors, but also among NMI tumors.[6] Further studies with gene expression profiling are awaited to refine these category further.
References
[6]
Yun SJ, Kim SK, Kim WJ. How do we manage high-grade T1 bladder cancer? Conservative or aggressive therapy? Investig Clin Urol. 2016;57(Suppl 1):S44−51 https://doi.org/10.4111/icu.2016.57.S1.S44