Kamat - Figure 32
Comprehensive Transcriptional Analysis of Early-stage Urothelial Carcinoma
FIG. 32: Another example of the utility of recognizing the subgroups of patients after BCG failure can be found when we look at gene expression profiling. Hedegaard and colleagues[29] analyzed early-stage urothelial carcinoma and performing similar subgrouping to that done by the Cancer Genome Atlas Research Network (TCGA) for muscle-invasive bladder cancer[30] and described three subclasses of NMI bladder cancer patients (the Lund classification).
References
Hedegaard J, Lamy P, Nordentoft I, et al. Comprehensive transcriptional analysis of early-stage urothelial carcinoma. Cancer Cell. 2016;30:27−42 http://dx.doi.org/10.1016/j.ccell.2016.05.004
The Cancer Genome Atlas Research Network. Comprehensivemolecular characterization of urothelial bladder carcinoma. Nature. 2014:507:315−22 http://www.nature.com/doifinder/10.1038/nature12965
