Kamat - Figure 27

Papillary Tumor

FIG. 27:  For true papillary recurrences in the Steinberg study,[25] the time point defining BCG unresponsive appeared a bit more definitive at 6 months. So for papillary tumors, ≥2 courses of BCG <6 months from the prior exposure (lowest line on the Kaplan-Meier curve in the Figure), appears to be the time point at which time these patients are truly BCG-unresponsive.

References

[25]

Steinberg RL, Thomas LJ, Mott SL, O'Donnell MA. Bacillus Calmette-Guérin (BCG) treatment failures with non-muscle invasive bladder cancer: a data-driven definition for BCG unresponsive disease. Bladder Cancer. 2016;2:215−24  https://dx.doi.org/10.3233%2FBLC-150039