Outcomes following acute hypercapnic exacerbations of COPD

Murphy - Figure 6

FIG. 6: Although NIV is currently being successfully implemented during acute exacerbations of COPD and showing successful outcomes, the prognosis for those patients following discharge remains poor, and this is true whether the data come from the UK (see the data from Murray et al[10] in this Figure), from Hong Kong,[11] or from the United States,[12] with survival rates of approximately 60% at 12 months across all of these studies. In other words, even though these data have been accumulated in very different healthcare settings, they confirm that the prognosis for these patients remains poor.

Murphy P. Chest 2017:00.

References

[10]

Murray I, Paterson E, Thain G, Currie GP. Outcomes following non-invasive ventilation for hypercapnic exacerbations of chronic obstructive pulmonary disease. Thorax. 2011;66:825−6. doi: 10.1136/thx.2010.152264.

[11]

Chung LP, Winship P, Phung S, et al. Five-year outcome in COPD patients after their first episode of acute exacerbation treated with non-invasive ventilation. Respirology. 2010;15:1084−91. doi: 10.1111/j.1440-1843.2010.01795.x.

[12]

Connors AF Jr, Dawson NV, Thomas C, et al. Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments). Am J Respir Crit Care Med. 1996;154(4 Pt 1):959−67. doi: 10.1164/ajrccm.154.4.8887592.