Murphy - Figure 44

Median BMI

FIG. 44: Comparing the baseline characteristics of the HOT-HMV patients[1] with those in the RESCUE trial[13] or the British Thoracic Society (BTS) audit data,[2] the enrollees in these trials were of similar age, with similar proportions of female patients. The BMI values in the RESCUE trial patients were slightly higher, but there were similar levels of preceding LTOT use. Both the RESCUE trial and the HOT-HMV data showed patients with significant previous exacerbations, although the severity of airflow obstruction was slightly more severe in HOT-HMV compared with patients in either the RESCUE trial or the more generic BTS audit (which looked at all patients attending UK hospitals with acute exacerbations of COPD).

Murphy P. Chest 2017:00.

References

[1]

Murphy P, Arbane G, Bourke S, et al. Effect of home non-invasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a randomized controlled trial. JAMA. In press.

[2]

Davidson C. 2010 Adult non-invasive ventilation audit summary report. London, UK: British Thoracic Society; 2010. https://www.brit-thoracic.org.uk/document-library/audit-and-quality-improvement/audit-reports/bts-adult-niv-audit-report-2010/ Accessed May 9, 2017. 

[13]

Struik FM, Sprooten RT, Kerstjens HAM, et al. Nocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomized, controlled, parallel-group study. Thorax. 2014;69:826−34. doi: 10.1136/thoraxjnl-2014-205126.