FIG. 33: The high-pressure strategy, as opposed to a high-intensity strategy, employed in HOT-HMV[1] was chosen because previous data from our own group, as shown in this Figure, had suggested that this provided similar control of hypoventilation with no evidence of over-ventilation (which can be associated with de-ventilation dyspnea and increased patient ventilator asynchrony).[16] This strategy was also based on the suggestion that high pressure, as opposed to high intensity ventilator support is associated with very similar levels of subjective and objective sleep quality.