Murphy - Figure 28
Target Population
FIG. 28: In summary, HOT-HMV was designed to randomize patients with severe COPD with a recent life-threatening exacerbation requiring NIV who presented with evidence of chronic hypercapnic respiratory failure with a PaCO2 >7 kPa in the recovery phase but without other significant causes of sleep-disordered breathing or respiratory failure.[1]
Murphy P. Chest 2017:00.
References
[1]
Murphy P, Arbane G, Bourke S, et al. Effect of home non-invasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a randomized controlled trial. JAMA. In press.