Murphy - Figure 23
Primary Diagnosis of Restrictive Lung Disease Causing Hypercapnia
FIG. 23: The trial also excluded patients who had a conventional reason to initiate NIV, eg, a primary diagnosis of a restrictive lung disease or significant symptomatic obstructive sleep apnea leading and contributing to patient morbidity.[1].
The trial also excluded patients with significant obesity, defined as BMI >35, so as to exclude a patient where obesity was playing a significant role is respiratory failure rather than COPD as the primary driver.
Murphy P. Chest 2017:00.
References
[1]
Murphy P, Arbane G, Bourke S, et al. Effect of home non-invasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a randomized controlled trial. JAMA. In press.