The impact of HMV on health-related quality of life (HRQOL) in patients with chronic respiratory failure was investigated in a German multicenter study that used various HRQOL questionnaires.^[4] The 3 left (hatched) columns show HRQOL assessed using the Severe Respiratory Insufficiency (SRI) questionnaire. This questionnaire was developed specifically for patients being treated with HMV due to chronic respiratory failure, and it is clear that there is an increase in HRQOL after 1 month of HMV that remained stable over the following 12 months.