Dreher - Figure 37
4. Nocturnal NIV Study: Struik et al
The null results of the RESCUE trial[18] were not anticipated and force the question, Why did patients not benefit from HMV in this trial? Looking at the PaCO2 values over time it is clear they significantly decreased in the patients receiving HMV. However, the PaCO2 values also decreased in the standard treatment group, who did not receive HMV, over time.
Dreher M. Chest 2017:00.
References
[18]
Struik FM, Sprooten RT, Kerstjens HAM, et al. Nocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomized, controlled, parallel-group study. Thorax. 2014;69:826−34. doi: 10.1136/thoraxjnl-2014- 205126.