5. Positive Pressure Ventilation Trial

Dreher - Figure 14

This Figure shows the results of the primary outcome parameter of the German multicenter study,^[5] mortality rate, which was significantly lower in the group receiving HMV compared with the control group. This study was the first to show that once HMV is employed to significantly reduce elevated CO₂ levels in patients with stable hypercapnic COPD, there is a positive impact on long-term survival.

Dreher M. Chest 2017:00.

References

[5]

Köhnlein T, Windisch W, Köhler D, et al. Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med. 2014;2:698–705. doi: 10.1016/S2213-2600(14)70153- 5.