Barter - Figure 7 - CETP inhibition on lipids levels - The Current Status and Future Development of CETP Inhibitors - Translating HDL Science to Clinical Practice

Barter - Figure 7 - CETP inhibition on lipids levels Text

This Figure summarizes the benefits of CETP inhibition:

It increases the concentration of HDL cholesterol and its main protein, apoA-I.
It decreases the concentration of LDL cholesterol, and surprisingly, for reasons we don’t understand, also decreases the concentration of the apo-B.
It decreases the cholesterol content of VLDL and thus reduces the atherogenicity of the VLDL.

Barter P. J Clin Lipidol. 2011; 5(6).