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Toth - Figure 4 - Genetics -1

FH is defined as an autosomal dominant trait with complete penetrance causing congenitally elevated levels of LDL cholesterol. There is a gene/dosage effect, with homozygotes having significantly greater elevations of LDL cholesterol and earlier cardiovascular disease (CVD) onset than heterozygotes.

Toth PP. J Clin Lipidol. 2011; 5(6).
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