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ZuWallack - Figure 19

Changes in Muscle Enzymes Following Exercise Training in COPD

FIG. 19:  More recently investigators demonstrated in biopsy specimens that after exercise training there was a significant increase in oxidative enzymes in the ambulatory muscles, showing that improvement in exercise capacity and reduction in lactate is associated with a metabolic effect in the muscles.[15,16]  In other words, this is a real physiologic effect.

ZuWallack R. Chest 2016; 00.

References

[15]

Maltais F, Simard AA, Simard C, et al. Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD. Am J Respir Crit Care Med. 1996;153:288293.

[16]

Maltais F, LeBlanc P, Whittom F, et al. Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD. Thorax. 2000;55:848–853.