Fig. 01 -

Title Slide

Fig. 02 -

Disclosure

Fig. 03 -

TSH-R Antibody Assays

Fig. 04 -

Binding versus Bio-assays

Fig. 05 -

Varieties

Fig. 06 -

Diagnostic Modalities

Fig. 07 -

Baseline Serum

Fig. 08 -

TSI Assay Utilization

Fig. 09 -

TSAB Bioassay Principle

Fig. 10 -

Mc4 TSHR

Fig. 11 -

Precision

Fig. 12 -

Novel Chimeric

Fig. 13 -

Sensitivity and Specificity

Fig. 14 -

Dose Response Curve

Fig. 15 -

Study Design

Fig. 16 -

Normal Serum

Fig. 17 -

Predictive Value

Fig. 18 -

Predict the Course

Fig. 19 -

TSI to TBI

Fig. 20 -

Bioassays

Fig. 21 -

Ranges of Bovine

Fig. 22 -

Blocking Activity

Fig. 23 -

K1-70 mAb

Fig. 24 -

Differentiates

Fig. 25 -

Different Ratios

Fig. 26 -

TSAb and TBAb

Fig. 27 -

173 TBAb

Fig. 28 -

Dose-Response Curves

Fig. 29 -

Analytical Performance

Fig. 30 -

Comparison

Fig. 31 -

ELISA and ABA

Fig. 32 -

Positivity of Low

Fig. 33 -

Positivity of Moderate

Fig. 34 -

Positivity of High

Fig. 35 -

Positivity in TBAb+

Fig. 36 -

Dilution Protocol

Fig. 37 -

Positivity in Untreated

Fig. 38 -

Positivity in GD

Fig. 39 -

Binding Assay Results

Fig. 40 -

TBAb Bioassay

Fig. 41 -

TSAb Bioassay

Fig. 42 -

Detection

Fig. 43 -

Kronus Elisa Assay

Fig. 44 -

Positivity in pts.

Fig. 45 -

Summary and Conclusions