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<h2>Underberg - Figure 2 - Key Points</h2>


<div class='figure_text' speaker='underberg' figure='2'>
      Familial hypercholesterolemia (FH) is a genetic disorder that is characterized clinically by extremely high levels of serum low-density lipoprotein cholesterol (LDL-C) and a family history of premature coronary heart disease (CHD) and atherosclerosis.&nbsp; Early detection and treatment is essential to reduce the morbidity and mortality associated with FH.&nbsp; Differences between men and women with this condition need to be understood.&nbsp; New National Lipid Association (NLA) recommendations support aggressive LDL-C lowering in patients with FH.&nbsp; Finally, despite recognized benefits of early detection and intervention, the challenges of under-diagnosis and under-treatment persist, including the need for newer therapies.<br style=\"\">  </div>
<div class='figuretext_source_identifier'>
  <span class="author">Underberg</span>
  <span class="publication">J Clin Lipidol.</span>
  <span class="identifier">2012;</span>
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  <a href="complete_references.php" class="noprint right resource_link buttonify" target_orig="_blank">Complete references for all slides</a>
  <h2>References</h2>
    <p>
    <span class="ref_num">[23]</span> Goldstein JL, et al. In: Scriver CR, et al. <i>The metabolic and molecular basis of inherited disease</i>. 8th ed. New York: McGraw-Hill, 2001;2863-2913.  </p>
    <p>
    <span class="ref_num">[24]</span> Horton, et al. <i>J Lipid Res</i>. 2009;50:S172-S177.  </p>
    <p>
    <span class="ref_num">[25]</span> Wiegman A, et al. <i>Lancet</i>. 2004;363:369–370.  </p>
    <p>
    <span class="ref_num">[26]</span> Marks D. et al. <i>Health Technology Assessment</i>, 2000;4(29).  </p>
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