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            <i>American Journal of Medicine</i>          </div>
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<h2><span style="font-size:12px;">Eikelboom - Evidence from the Randomized Trials - Figure 4</span><br />Incidence of VTE Recurrence</h2>



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What is the risk of recurrent VTE? &nbsp;If a patient has a transient or reversible risk factor, the best estimates suggest that the annual risk of recurrence is around 1% to 4% (<b>Figure 4</b>), although some researchers have suggested that around 3% is the best estimate.<span class="ref_num">[2]</span>&nbsp;On the other hand, &nbsp;in patients with continuing risk factors -- such as those &nbsp;already mentioned (eg, prolonged immobility), others such as cancer, or those with no identifiable risk factors -- the risk of recurrence is approximately 10%.
 <font color="#000000" face="Times New Roman" size="3"><span style='color: black; font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: "Times New Roman";'><b style="mso-bidi-font-weight: normal;">Eikelboom J. <i style="mso-bidi-font-style: normal;">Am J Med</i> 2013; </b>published on-line at </span><span style='color: rgb(0, 0, 102); font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: AdvOT3c2d9f11;'>http://education.amjmed.com/00000.</span><u1:p></u1:p></font>&nbsp;</p>
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    <span class="ref_num">[2]</span> Kearon C. Natural history of venous thromboembolism. <i>Circulation</i>. 2003;107(23 Suppl 1):122-130.  </p>
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