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            <i>American Journal of Medicine</i>          </div>
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<h2><span style="font-size:12px;">Eikelboom - Evidence from the Randomized Trials - Figure 24</span><br />AMPLIFY Ext: VTE or VTE-related Deaths</h2>



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The primary results of apixaban for the outcome of VTE or VTE-related mortality in the AMPLPIFY-EXT trial showed that both doses of apixaban very substantially reduced the risk of recurrence by around 80% (<b>Figure 24</b>) .<span class="ref_num">[14]&nbsp; <font color="#000000" face="Times New Roman" size="3"><span style='color: black; font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: "Times New Roman";'><b style="mso-bidi-font-weight: normal;">Eikelboom J. <i style="mso-bidi-font-style: normal;">Am J Med</i> 2013; </b>published on-line at </span><span style='color: rgb(0, 0, 102); font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: AdvOT3c2d9f11;'>http://education.amjmed.com/00000.</span><u1:p></u1:p></font>&nbsp;</span><br class="aloha-end-br"></p>
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  <h2>References</h2>
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    <span class="ref_num">[14]</span> Agnelli G, Büller HR, Cohen A, et al; AMPLIFY-EXT Investigators. Apixaban for extended treatment of venous thromboembolism. <i>N Engl J Med</i>. 2013;368:699-708.  </p>
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