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            <i>American Journal of Medicine</i>          </div>
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<h2><span style="font-size:12px;">Eikelboom - Evidence from the Randomized Trials - Figure 15</span><br />RE-MEDY: VTE or Related Death</h2>



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As was the case in RE-COVER I. the result for the primary outcome of RE-MEDY for&nbsp;the initial treatment of&nbsp;acute VTE <font color="#000000" face="Times New Roman" size="3"><span style='color: black; font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: "Times New Roman";'><b style="mso-bidi-font-weight: normal;"></b></span><u1:p></u1:p></font>was statistically similar in patients treated with <span class="GINGER_SOFATWARE_spelling" ginger_sofatware_uiphraseguid="8608eda3-716c-4bcd-83d3-31b61cf746ef">dabigatran</span> and those treated with <span class="GINGER_SOFATWARE_spelling" ginger_sofatware_uiphraseguid="8608eda3-716c-4bcd-83d3-31b61cf746ef">warfarin, although the event curves</span> (<b>Figure 15</b>)<span class="ref_num">[9]</span> appear to show a slight trend toward better efficacy with <span class="GINGER_SOFATWARE_spelling" ginger_sofatware_uiphraseguid="8608eda3-716c-4bcd-83d3-31b61cf746ef">warfarin.&nbsp; <font color="#000000" face="Times New Roman" size="3"><span style='color: black; font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: "Times New Roman";'><b style="mso-bidi-font-weight: normal;">Eikelboom J. <i style="mso-bidi-font-style: normal;">Am J Med</i> 2013; </b>published on-line at </span><span style='color: rgb(0, 0, 102); font-family: "Helvetica","sans-serif"; font-size: 9pt; mso-fareast-font-family: Times; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA; mso-bidi-font-size: 10.0pt; mso-bidi-font-family: AdvOT3c2d9f11;'>http://education.amjmed.com/00000.</span><u1:p></u1:p></font>&nbsp;</span><br class="aloha-end-br"></p>
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    <span class="ref_num">[9]</span> Schulman S, Kearon C, Kakkar AK, et al; for the RE-MEDY and the RE-SONATE Trials Investigators. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. <i>N Engl J Med</i>. 2013;368:709-718.  </p>
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