This Figure presents a tabular comparison of factors that physicians will need to consider in choosing to replace warfarin in their patients with one of these new anticoagulation agents.  Physicians will have to consider drug biologic half-life, drug interaction potentials, renal excretion issues, hepatic metabolism, GI disorders, and ischemic risk signals.

 Reiffel JA. Am J Med 2013; 126: 00-00.