In terms of bleeding outcomes, the Figure shows that all except gastrointestinal bleeds were significantly reduced with apixaban versus warfarin.  Intracranial bleeding, in particular, was reduced by almost 60%. In contrast to the other approved factor Xa inhibitor, however, GI bleeding was not increased, highlighting that there are subtle differences among the agents. 

 Reiffel JA. Am J Med 2013; 126: 00-00.