James A. Reiffel, MD - Novel Oral Anticoagulants - Figure 26

Outcome Events in Patients Undergoing Cardioversion

This Figure repeats the information presented by Dr. Rothman. The point of this post hoc analysis is that the anticoagulant action of dabigatran begins within 2 hours.  At present both the guidelines and customary clinical practice lead to anticoagulating patients for 3 weeks prior to a scheduled cardioversion.[111] Actually, with warfarin it probably requires >3 weeks to establish a stable INR in the patient – perhaps 4, 5, 6, 8 weeks.  Therefore this represents another significant benefit with dabigatran -- its predictability.

 Reiffel JA. Am J Med 2013; 126: 00-00.