The Figure shows the inclusion criteria for RE-LY.[108] Although these criteria did not exactly parallel the CHADS₂ or CHA₂DS₂-VASc score criteria, there was significant congruence.  Of note is that low-dose daily aspirin was allowed for all these patients on anticoagulation therapy, although relatively few patients were on aspirin. In addition, patients were allowed to take antiplatelet clopidogrel, although only about 6% did so.

 Reiffel JA. Am J Med 2013; 126: 00-00.