Berman - Figure 12 - Screening & Triage by HPV DNA Testing Text

Berman - Figure 12 - Screening & Triage by HPV DNA Testing

Screening and triage by HPV testing. 

  • To recap, if both Pap and HPV DNA tests are negative, we can repeat co-testing in 5 years - regardless of sexual history.  

  • Even if my patient has a new partner or many new partners and potentially has been infected by HPV.  Even if she had a Pap-negative/HPV-negative test today, and she has a new partner tomorrow, there is no need to rescreen her for 5 years, because most infections clear in 8-9 months in women of all ages.  

  • In 24 months, the majority of infections have cleared, and even if pre cancer develops, we do not see progression to invasive disease in a short period of time.  

  • So, sexual history is not a factor in when women are rescreened, and if HPV is negative after co testing, it is safe then to wait 5 years.

  • Finally, there is no need to resume screening in women over age 65 even if they become sexually active.