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Jin - Figure 16 - Italian NTCC Trial: Results

Italy NTSCC Trial - Results (continued):  This slide shows you the sensitivity and the specificity of liquid based
cytology and HPV testing in the study arm:

  • HPV testing is more sensitive for CIN 2 or worse (i.e., CIN2+), lesions than ASC-US or worse (i.e., ASC-US+)
    using liquid-based cytology. 
  • With very similar specificity when CIN 2+ or CIN 3+ are used as endpoints.

Therefore, adding HPV testing in screening really improved clinical sensitivity significantly.  

Complete references for all slides

References

[51] Ronco, G. et al. Human Papillomavirus testing and liquid-based cytology: results at recruitment from the new technologies for cervical cancer randomized controlled trial. J. Natl Cancer Inst 2006; 98(11):765-774

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